- Extrahepatic Bile Duct Hepatocellular Carcinoma Presenting as Obstructive Jaundice
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Ju Hyun Shim, Joong-Won Park, Sung-Sik Han, Joon-Il Choi, Seong Hoon Kim, Sang Jae Park, Eun Kyung Hong, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2008;8(1):51-54. Published online June 30, 2008
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- Obstructive jaundice is a rare initial symptom of hepatocellular carcinoma (HCC) patients. We herein report a
patient with extrahepatic bile duct HCC mimicking common bile duct (CBD) cancer. A 55-year-old woman with
no risk factors developed jaundice of the obstructive type. On dynamic computed tomography, a low attenuated
mass located in the lumen of CBD with the invasion of right posterior hepatic parenchyma was identified. After
percutaneous transhepatic biliary drainage, we performed hepatectomy. Pathologic examination of the lesion
confirmed the diagnosis of hepatocellular carcinoma with biliary cell differentiation extended in the CBD.
- Successful Resection of Modified UICC stage Ⅳa Hepatocellular Carcinoma after Arterial Chemoembolization & Radiation Therapy: A Case Report
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Min An, Joong-Won Park, Jung A Shin, Tae Hyun Kim, Seong-Hoon Kim, Sang-Jae Park, Woo Jin Lee, Eun Kyung Hong, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2006;6(1):56-59. Published online June 30, 2006
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- Surgical resection is not candidate for advanced stage hepatocellular cacinoma with portal vein thrombosis, but
transcatheter arterial chemoembolization (TACE) or radiotherapy can be considered as palliative treatment option.
We experienced a 44-old-male who has stage Ⅳa hepatocellular carcinoma. We performed TACE and 3-dimensional
conformal radiotherapy for hepatocellular carcinoma and portal vein thrombosis. Because follow up image
study showed no viable tumor, we then performed surgical resection. Surgical specimen also showed complete
tumor necrosis.
- Treatment of Hepatocellular Carcinoma with Arterioportal Shunt after Percutaneous Needle Biopsy
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Sang-Hyung Cho, Jae-Hee Cheon, Hong-Suk Park, Seong-Hoon Kim, Sang-Jae Park, Woo-Jin Lee, Eun-Kyung Hong, Joong-Won Park, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2004;4(1):20-23. Published online June 30, 2004
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- A 51-year-old male was referred to our hospital for further evaluation and treatment of a liver mass. He was a heavy alcoholic. Laboratory findings revealed that anti-HCV was positive, and AFP is below 400 ng/mL. We performed CT scan that showed multiple nodules in the right lobe. Among them, the nodule in the segment Ⅷ showed incomplete enhancement at the arterial phase. Hence, we performed percutaneous needle biopsy for this nodule, and pathologically proved to hepatocellular carcinoma of Edmonson-Steiner grade Ⅱ/Ⅳ. We performed transcatheter arterial chemoembolization(TACE) for multiple hepatocellular carcinomas. Angiography showed nodular tumor staining and arterioportal shunt and arteriovenous shunts at the biopsy site in the segment Ⅷ. We occluded the shunts by using Lipiodol and gelform mixtures and then performed TACE. After TACE, angiography did not show either residual tumor staining or arterioportal and arteriovenous shunts.
- A Resected Case of Early Hepatocellular Carcinoma
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Sang-Jae Park, Joong-Won Park, Seong-Hun Kim, Soon-Ae Lee, Young-Hun Kim, Eun-Kyoung Hong, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2004;4(1):33-38. Published online June 30, 2004
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- A 35 year-old male patient admitted due to epigastric pain for 1 month. He was heavy drinker and spider angioma was obserbed in physical examination. HBsAb, anti-HBs Ab and anti-HCV Ab were all negative and AFP level was normal. AST/ALT were elevated to 178 IU/L and 107 IU/L, respectively. At ultrasonography, CT and MRI, a 2 cm, hypervascular mass was detected in the segment Ⅵ. Segmentectomy of the segment Ⅵ was performed. Tumor size 1.7 cm in maximum diameter and the Edmondson and Steiners grade Ⅰ. High-grade dysplasia was present in the periphery of hepatocellular carcinoma (nodule-in-nodule). Microvascular invasion was not observed and background liver was cirrhotic. He was discharged 10 days after operation without any problem and there has been no evidence of recurrence for the 2 years postoperatively.
- A Case of Early Recurrence of Hepatocellular Carcinoma after Curative Hepatic Resection
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Sang-Hyung Cho, Jae-Hee Cheon, Hong-Suk Park, Seong-Hoon Kim, Sang-Jae Park, Woo-Jin Lee, Eun-Kyung Hong, Joong-Won Park, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2004;4(1):55-58. Published online June 30, 2004
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- A 52-year-old male was referred to our hospital for further evaluation and treatment of known hepatocelluar carcinoma. He did not have risk factors for hepatocellular carcinoma, such as hepatitis virus infection, alcohol abuse and occupational history. We performed CT scan that showed a single nodule with a diameter of 4 cm in the segment Ⅴ. MR imaging showed the same nodule in the segment Ⅴ without any additional nodule in the liver. We performed segmentectomy for the segment Ⅴ, Ⅵ, and Ⅶ. Five months later, follow-up CT scan showed disseminated hypervascular nodules involving the remaining liver. Hepatic angiography also showed multiple hypervascular nodules in the remaining liver, indicating early recurrence by intrahepatic metastasis. We then performed transcatheter arterial chemoembolization (TACE). At present, this patient underwent TACE for ten times, but was still found to have new intrahepatic metastases, tumor invasion to the portal vein and lymph node metastasis in the peripancreatic area.
- A Case of High Grade Dysplastic Nodule, Diagnosed as Hepatocelluar Carcinoma before Operation
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Sang-Hyung Cho, Joong-Won Park, Hyun-Bae Son, Seong-Hoon Kim, Hyun-Jung Jang, Hong-Suk Park, Woo-Jin Lee, Sang-Jae Park, Eun-Kyung Hong, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2003;3(1):57-60. Published online July 31, 2003
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- A 58-years-old male was referred to our hospital for further evaluation and treatment due to hepatic mass which was found on US. He was a heavy drinker and there was no evidence of abnormal finding in liver function test including HBs Ag and Anti-HCV Ab negative. Liver CT revealed an enhancing hepatic mass on arterial phase. we had confirmed hepatocellular carcinoma by sono-guided liver biopsy, and so performed left lobectomy. After operation, We diagnosed the resected liver specimen not hepatocellular carcinoma but high grade dysplastic nodule by several immunohistochemical staining. There was no evidence of recurrence during 5-month follow-up.
- A Case of Atypical Imaging Finding for Hepatocellular Carcinoma
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Sang-Hyung Cho, Seong-Hoon Kim, Hyun-Jung Jang, Hong-Suk Park, Woo-Jin Lee, Sang-Jae Park, Joong-Won Park, Eun-Kyung Hong, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2003;3(1):77-79. Published online July 31, 2003
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- A 62-year-old male was referred to our hospital for further evaluation and treatment due to hepatocellular carcinoma. He was performed to TACE once. Threre was no evidence of abnormal finding except HBs Ag positive. We performed four times of TACE. Another hepatic mass was found on Liver CT which was observed in delyed phase not in arterial phase, portal phase. We diagnosed hepatocellular carcinoma by sono-guided Liver biopsy and radiofrequency ablation was performed because of no response to further TACE. There wad no evidence of recurring during 3-month follow-up.
- A Case of Well-differenciatied Hepatocellular Carcinoma in Dysplastic Nodule
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Jeon-Ho Yang, Joong-Won Park, Hyun-Jung Jang, Hong-Suk Park, Sang-Jae Park, Eun Kyung Hong, Young-Soo Moon, Chang-Min Kim
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Journal of the Korean Liver Cancer Study Group. 2002;2(1):96-100. Published online July 31, 2002
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- A 35-year-old male patient was referred to our hospital, because a hepatic mass had been found on CT at another hospital. He was a heavy drinker, but he has never experienced any significant disease so far. Anti-HBs Ab, HBs Ag and anti-HCV Ab were negative. AFP level was normal. Triphasic liver CT scan revealed a 1.9 cm-sized, well-enhanced lesion at S6 on arterial phase. This lesion becomes isoattenuation on portal phase and slightly enhancing lesion on delayed phase. SPIO MRI scan reavealed a 1.9 cm-sized lesion with high signal intensity at S6 on T2WI. Precontrast ultrasonography revealed a enhancing nodule with mosaic pattern on S6 Contrast-enhanced ultrasonography revealed a centrally enhancing nodule early phase that showed washout on delayed phase. We had considered as the hepatocellular carcinoma. Segmentectomy of S6 for diagnosis and treatment was performed. We confirmed it to be well-differenciated hepatocellular carcinoma in dysplastic nodule. There was no evidence of recurrence during 9-month follow-up.
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